The ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province
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چکیده
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Plasma interleukin‐22 levels are associated with prediabetes and type 2 diabetes in the Han Chinese population
AIMS/INTRODUCTION The objective of the present study was to investigate the relationship between plasma interleukin-22 (IL-22) levels and prediabetes or type 2 diabetes, and search the relevance between plasma concentrations of IL-22 and selected diabetes risk factors in Chinese people. MATERIALS AND METHODS The Han Chinese origin men and women participants were recruited in our study during ...
متن کاملSingle nucleotide polymorphisms on SHIP2 is associated with Type 2 diabetes mellitus in Chinese Han population.
OBJECTIVE Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by insulin resistance in the target tissue of insulin with insufficient insulin secretion in pancreatic β-cells. Src homology 2-containing 5'-inositol phosphatase 2 (SHIP2) is a lipid phosphatase that hydrolyzes PI3-kinase product PI(3,4,5)P3 to PI(3,4)P2, which contributes to the negative regulation of insulin signali...
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15 صفحه اولGenetic variants associated with lean and obese type 2 diabetes in a Han Chinese population
Type 2 diabetes (T2D) is highly phenotypically heterogeneous. Genetics of the heterogeneity of lean and obese T2D is not clear. The aim of the present study was to identify the associations of T2D-related genetic variants with the risks for lean and obese T2D among the Chinese Han population. A case-control study consisting of 5338 T2D patients and 4663 normal glycemic controls of Chinese Han r...
متن کاملA common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals
BACKGROUND Several studies have shown that common variants in the MTNR1B gene were associated with fasting glucose level and type 2 diabetes. The purpose of this study was to examine whether tagging single nucleotide polymorphisms (SNPs) in the MTNR1B region were associated with type 2 diabetes and related traits in a Han Chinese population. METHODS We investigated the association of polymorp...
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ژورنال
عنوان ژورنال: International Journal of Endocrinology
سال: 2020
ISSN: 1687-8345,1687-8337
DOI: 10.1155/2020/1621239